Publikationen

Jan-Peter Hildebrandt, Horst Bleckmann, Uwe Homberg
Penzlin - Lehrbuch der Tierphysiologie
8. Auflage (2015)
ab 2015
  • Hildebrandt, J.-P.; Wiesenthal, A.A.; Müller, C. (2018) Phenotypic plasticity in animals exposed to osmotic stress - is it always adaptive? Bioessays 40 (11): 1800069 (doi: 10.1002/bies.201800069)
  • Wiesenthal, A.A.; Müller, C.; Hildebrandt, J.-P. (2018) Potential modes of range shifts in euryhaline snails from the Baltic Sea and fresh water lakes in northern Germany. Hydrobiologia 811: 339–350
  • Ziesemer, S.; Eiffler, I.; Schönberg, A.; Müller, C.; Hochgräfe, F.; Beule, A.; Hildebrandt, J.-P. (2018) Staphylococcus aureus alpha-toxin induces actin filament remodeling in human airway epithelial model cells. Am J Respir Cell Mol Biol 58: 482-491 (Current Issue Highlight)
  • Müller, C.; Haase, M.; Lemke, S.; Hildebrandt, J.-P. (2017) Hirudins and hirudin-like factors in Hirudinidae: implications for function and phylogenetic relationships. Parasitol Res 116: 313-325
  • Baaske, R.; Richter, M.; Möller, N.; Ziesemer, S.; Eiffler, I.; Müller, C.; Hildebrandt, J.-P. (2016) ATP release from human airway epithelial cells exposed to Staphylococcus aureus alpha-toxin. Toxins 8: 365; DOI 10.3390/toxins8120365
  • Eiffler, I.; Behnke, J.; Ziesemer, S.; Müller, C.; Hildebrandt, J.-P. (2016) Staphylococcus aureus alpha-toxin-mediated cation entry depolarizes membrane potential and activates p38 MAP kinase in airway epithelial cells. Am J Physiol Lung Cell Mol Physiol 311: L676-L685
  • Lemke, S.; Müller, C.; Hildebrandt, J.-P. (2016) Be ready at any time: postprandial synthesis of salivary proteins in salivary gland cells of the haematophagous leech, Hirudo verbana. J Exp Biol 219 (8): 1139-1145
  • Müller, C.; Mescke, K.; Liebig, S.; Mahfoud, H.; Lemke, S.; Hildebrandt, J.-P. (2016) More than just one: Multiplicity of hirudins and hirudin-like factors in the medicinal leech, Hirudo medicinalis. Mol Genet Genomics 291(1): 227-240
  • Hildebrandt, J.-P. (2015) Pore-forming virulence factors of Staphylococcus aureus destabilize epithelial barriers - effects of alpha-toxin in the early phases of airway infection. AIMS Microbiology 1 (1): 11-36
  • Hildebrandt, J.-P.; Bleckmann, H.; Homberg, U. (2015) Penzlin - Lehrbuch der Tierphysiologie. 8. Auflage. Springer-Spektrum, Heidelberg
  • Richter, E.; Harms, M.; Ventz, K.; Gierok, P.; Chilukoti, R.K.; Hildebrandt, J.-P.; Mostertz, J.; Hochgräfe, F. (2015) A multi-omics approach identifies key hubs associated with cell type-specific responses of airway epithelial cells to staphylococcal alpha-toxin. PLoS One 10 (3): e0122089
  • Hermann, I.; Räth, S.; Ziesemer, S.; Volksdorf, T.; Dress, R.J.; Gutjahr, M.; Müller, C.; Beule, A.G.; Hildebrandt, J.-P. (2015) Staphylococcus aureus-hemolysin A disrupts cell-matrix adhesions in human airway epithelial cells. Am J Respir Cell Mol Biol 52 (1): 14-24
2010 - 2014
  • Will, K.; Kuzinski, J.; Palin, M.-F.; Hildebrandt, J.-P.; Rehfeldt, C. (2014) A second look at leptin and adiponectin actions on the growth of primary porcine myoblasts under serum-free conditions. Arch Tierz 57 (29): 1-10. DOI 10.7482/0003-9438-57-029
  • Gierok, P.; Harms, M.; Richter, E.; Hildebrandt, J.-P.; Lalk, M.; Mostertz, J.; Hochgräfe, F. (2014) Staphylococcus aureus alpha-toxin mediates general and cell type-specific changes in metabolite concentrations of immortalized human airway epithelial cells. PLoS One 9 (4): e94818
  • Lemke, S.; Müller, C.; Lipke, E.; Uhl, G.; Hildebrandt, J.-P. (2013) May salivary gland secretory proteins from hematophageous leeches (Hirudo verbana) reach pharmacologically relevant concentrations in the vertebrate host? PLoS One 8 (9): e73809
  • Rohlfing, A.-K.; Trescher, K.; Hähnel, J.; Müller, C.; Hildebrandt, J.-P. (2013) Partial hepatectomy in rats results in immediate down-regulation of p27Kip1 in residual liver tissue by transcriptional and post-translational processes. Front. Physiol. 4: 139. doi: 10.3389/fphys.2013.00139
  • Räth, S.; Ziesemer, S.; Witte, A.; Konkel, A.; Müller, C.; Hildebrandt, P.; Völker, U.; Hildebrandt, J.-P. (2013) S. aureus hemolysin A-induced IL-8 and IL-6 release from human airway epithelial cells is mediated by activation of p38- and Erk-MAP kinases and additional, cell-type specific signalling mechanisms. Cell. Microbiol. 15: 1253-1265. DOI 10.1111/cmi.12113
  • Franz, M.; Eiden, M.; Balkema-Buschmann, A.; Greenlee, J.; Schatzl, H.M.; Fast, C.; Richt, J.; Hildebrandt, J.-P.; Groschup, M.H. (2012) Detection of PrPSc in peripheral tissues of clinically affected cattle after oral challenge with bovine spongiform encephalopathy. J. Gen. Virol. 93: 2740-2748
  • Hildebrandt, J.-P.; Lemke, S. (2011) Small bite, large impact - saliva and salivary molecules in the medicinal leech, Hirudo medicinalis. Naturwissenschaften 98: 995-1008
  • Asmat, T.M.; Agarwal, V.; Räth, S.; Hildebrandt, J.-P.; Hammerschmidt, S. (2011) Streptococcus pneumoniae infection of host epithelial cells via polymeric immunoglobulin receptor transiently induces calcium release from intracellular stores. J. Biol. Chem. 286: 17861-17869
  • Symanowski, F.; Hildebrandt, J.-P. (2010) Differences in osmotolerance in freshwater and brackish water populations of Theodoxus fluviatilis (Gastropoda: Neritidae) are associated with differential protein expression. J. Comp. Physiol. B 180: 337-346
2005 - 2009
  • Schwarzstein, M.; Hildebrandt, J.-P. (2009) Thermoregulation bei Vertebraten und die evolutive Entstehung der Endothermie. Shaker Verlag, Aachen, ISBN 978-3-8322-8344-5
  • Below, S.; Konkel, A.; Zeeck, C.; Müller, C.; Kohler, C.; Engelmann, S.; Hildebrandt, J.-P. (2009) Virulence factors of Staphylococcus aureus induce Erk-MAP kinase activation and c-Fos expression in S9 and 16HBE14o- human airway epithelial cells. Am. J. Physiol. Lung Cell. Mol. Physiol. 296: L470-L479
  • Eichstaedt, S.; Gäbler, K.; Below, S.; Müller, C. Kohler, C.; Engelmann, S.; Hildebrandt, P.; Völker, U.; Hecker, M.; Hildebrandt, J.-P. (2009) Effects of Staphylococcus aureus-hemolysin A on calcium signalling in immortalized human airway epithelial cells. Cell Calcium 45: 165-176
  • Eichstaedt, S.; Gäbler, K.; Below, S.; Müller, C.; Hildebrandt, J.-P. (2008) Phospholipase C-activating plasma membrane receptors and calcium signalling in immortalized human airway epithelial cells. J. Recept. Signal Transduction 28: 591-612
  • Do Minh, Si; Below, S.; Müller, C.; Hildebrandt, J.-P. (2008) Novel mammalian cell lines expressing reporter genes for the detection of environmental chemicals activating endogenous aryl hydrocarbon receptors (ArhR) or estrogen receptors (ER). Toxicology in Vitro 22: 1935-1947
  • Müller, C.; Sendler, M.; Hildebrandt, J.-P. (2006) Downregulation of aquaporins 1 and 5 in nasal gland by osmotic stress in ducklings, Anas platyrhynchos - implications for the production of hypertonic fluid. J. Exp. Biol. 209: 4067-4076
  • Mau, M.; Müller, C.; Langbein, J.; Rehfeldt, C.; Hildebrandt, J.-P.; Kaiser, T.M. (2006) Adhesion of bovine and goat salivary proteins to dental enamel and silicate. Arch. Tierz. 49: 439-446
  • Rohlfing, A.-K.; Schill, T.; Müller, C.; Hildebrandt, P.; Prowald, A.; Hildebrandt, J.-P. (2005) Attenuation of cell cycle regulator p27Kip1 expression in vertebrate epithelial cells mediated by extracellular signals in vivo and in vitro. J. Comp. Physiol. B 175: 511-522
  • Kusche, K.; Bangel, N., Müller, C.; Hildebrandt, J.-P.; Weber, W.-M. (2005) Molecular cloning and sequencing of the Na+/K+-ATPase alpha-subunit of the medical leech Hirudo medicinalis (Annelida) - implications for modelling protostomian evolution. J. Zool. Syst. Evol. Res. 43: 339-342
  • Klopfleisch, R.; Müller, C.; Polster, U.; Hildebrandt, J.-P.; Teifke, J.P. (2005) Granulomatous inflammation of salt glands in ducklings (Anas platyrhynchos) associated with intralesional Gram-negative bacteria. Avian Pathol. 34 (3): 233-237
  • Hildebrandt, J.-P. (2005) Neubearbeitung der Kapitel "Säure/Basen-Regulation", "Exkretion" und "Ionen- und Osmoregulation" für die 7. Auflage des Lehrbuches Heinz Penzlin: Lehrbuch der Tierphysiologie, Spektrum Akademischer Verlag, Heidelberg
  • Klann, A.; Levy, G.; Lutz, I.; Müller, C.; Kloas, W.; Hildebrandt, J.-P. (2005) Estrogen-like effects of UV screen 3-(4-methylbenzylidene)-camphor (4-MBC, Eusolex 6300®) on cell proliferation and gene induction in mammalian and amphibian cells. Environm. Res. 97: 274-281
2000 - 2004
  • Krohn, M.; Hildebrandt, J.-P. (2004) Crosstalk of phosphoinositide- and cyclic nucleotide-dependent signaling pathways in differentiating avian nasal gland cells. J.Comp.Physiol. B 174: 461-470
  • Müller, C.; Hildebrandt, J.-P. (2003) Salt glands - the perfect way to get rid of too much sodium chloride. Biologist 50 (6): 255-258
  • Stephenson, S.; Müller, C.; Jiang, M.; Perego, M. (2003) Molecular analysis of Phr peptide processing in Bacillus subtilis. J. Bacteriology 185: 4861-4871
  • Hildebrandt, J.-P. (2001) Coping with excess salt: adaptive functions of extrarenal osmoregulatory organs in vertebrates. Zoology 104: 209-220
  • Müller, C.; Lauf, U.; Herrmann, H. (2001) The inverted repeats of IS1384, a newly described insertion sequence from Pseudomonas putida strain H, represent the specific target for integration of IS1383. Mol.Genet.Genomics 265: 1004-1010
  • Petruschka, L.; Burchhardt, G.; Müller, C.; Weihe, C.; Herrmann, H. (2001) The cyo operon of Pseudomonas putida is involved in carbon catabolite repression of phenol degradation. Mol.Genet.Genomics 266: 199-206
  • Hildebrandt, J.-P.; Prowald, A. (2000) Ca2+ and p38 MAP kinase regulate mAChR-mediated c-Fos expression in avian exocrine cells. Am.J.Physiol.Cell Physiol. 278: 879-884
1995 - 1999
  • Shuttleworth, T.J.; Hildebrandt, J.-P. (1999) Vertebrate salt glands: short- and long-term regulation of function. J.Exp.Zool. 283: 689-701
  • Bentz, C.; Schwarz, M.; Hildebrandt, J.-P. (1999) Cytosolic pH affects DNA-synthesis in nasal gland cells of osmotically stressed ducklings, Anas platyrhynchos. Zoology 102: 10-17
  • Hildebrandt, J.-P.; Gerstberger, R.; Schwarz, M. (1998) In vivo and in vitro induction of c-fos in avian exocrine salt gland cells. Am.J.Physiol. 275: C951-C957
  • Hildebrandt, J.-P.; Plant, T.D.; Meves, H. (1997) The effects of bradykinin on K+ currents in NG108-15 cells treated with U73122, a phospholipase C inhibitor, or neomycin. Br.J.Pharmacol. 120: 841-850
  • Hildebrandt, J.-P. (1997) Changes in Na+/K+-ATPase expression during adaptive cell differentiation in avian nasal salt gland. J.Exp.Biol. 200: 1895-1904
  • Hildebrandt, J.-P.; Hildebrandt, P. (1997) Lysophosphatidic acid depletes intracellular calcium stores different from those mediating capacitative calcium entry in C6 rat glioma cells. Glia 19: 67-73
  • Hildebrandt, J.-P. (1996) [Malaria--biological aspects of an infectious disease of importance to humans].[Article in German] Naturwissenschaften 83: 359-369
  • Thévenod, F.; Hildebrandt, J.-P.; Striessnig, J.; de Jonge, H.R.; Schulz, I. (1996) Chloride and potassium conductances of mouse pancreatic zymogen granules are inversely regulated by a approximately 80-kDa mdr1a gene product. J.Biol.Chem. 271: 3300-3305
  • Thévenod, F.; Striessnig, J.; Haase, W.; Anderie, I.; Hildebrandt, J.-P.; de Jonge, H.R.; Schulz, I. (1996) Functional relationship between a 65-kD mdr1 P-glycoprotein and ATP-activated chloride conductance in pancreatic zymogen granule membranes. Cell.Physiol.Biochem. 6: 91-104
  • Bentz, C.; Hildebrandt, J.-P. (1995) Adaptive differentiation of avian exocrine cells alters their pHi response to mAChR activation. Am.J.Physiol. 268: C944-C951
  • Hildebrandt, J.-P. (1995) Lysophosphatidic acid induces inositol phosphate and calcium signals in exocrine cells from the avian nasal salt gland. J.Membr.Biol. 144: 49-58
1990 - 1994
  • Hildebrandt, J.-P.; Shuttleworth, T.J. (1994) Muscarinic receptor characterization in differentiating avian exocrine cells. Am.J.Physiol. (Regulatory Integrative Comp.Physiol. 35) 266: R674-R681
  • Hildebrandt, J.-P.; Shuttleworth, T.J. (1993) A Gq-type G protein couples muscarinic receptors to inositol phosphate and calcium signaling in exocrine cells from the avian salt gland. J.Membr.Biol. 133: 183-190
  • Hildebrandt, J.-P.; Shuttleworth, T.J. (1992) Calcium sensitivity of inositol 1,4,5-trisphosphate metabolism in exocrine cells from the avian salt gland. Biochem.J. 282: 703-710
  • Hildebrandt, J.-P.; Zerbst-Boroffka, I. (1992) Osmotic and ionic regulation during hypoxia in the medicinal leech, Hirudo medicinalis L. J.Exp.Zool. 263: 374-381
  • Hildebrandt, J.-P. (1992) External CO2 levels influence energy yielding metabolic pathways under hypoxia in the leech, Hirudo medicinalis. J.Exp.Zool. 261: 379-386
  • Hildebrandt, J.-P.; Shuttleworth, T.J. (1991) Inositol phosphates and [Ca2+]i signals in a differentiating exocrine cell. Am.J.Physiol. (Cell Physiol. 30) 261: C210-C217
bis 1989
  • Hildebrandt, J.-P.; Zerbst-Boroffka, I. (1988) Effect of salt and volume loading on the circulation in the leech, Hirudo medicinalis L. J.Comp.Physiol. B 158: 553-557
  • Hildebrandt, J.-P. (1988) Circulation in the leech, Hirudo medicinalis L. J.Exp.Biol. 134: 235-246